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ECDCECDC update: 9 confirmed + 2 probable + 3 deaths in Andes hantavirus cruise ship clusterMay 12info.gouv.frFrance mandates 42-day hospital quarantine for 22 close contacts of MV Hondius hantavirus caseMay 11ECDCShip MV Hondius docks in Tenerife; 147 passengers and crew begin mandatory 42-day quarantineMay 10WHOWHO Disease Outbreak News #600: 6 confirmed, 2 probable, 3 deaths — hantavirus linked to cruise shipMay 8CDCCDC Health Alert Network #528: multi-country hantavirus cluster linked to Antarctic expedition cruiseMay 8Sanidad EspañaSanidad (Spain): informe de situación brote virus Andes en crucero — un caso confirmado provisionalMay 8RIVMRIVM: 28 Dutch passengers from MV Hondius under home quarantine — GGD contact tracing underwayMay 7Argentina MSalArgentina refuerza la vigilancia epidemiológica de hantavirus tras el brote del MV HondiusMay 6ECDCECDC update: 9 confirmed + 2 probable + 3 deaths in Andes hantavirus cruise ship clusterMay 12info.gouv.frFrance mandates 42-day hospital quarantine for 22 close contacts of MV Hondius hantavirus caseMay 11ECDCShip MV Hondius docks in Tenerife; 147 passengers and crew begin mandatory 42-day quarantineMay 10WHOWHO Disease Outbreak News #600: 6 confirmed, 2 probable, 3 deaths — hantavirus linked to cruise shipMay 8CDCCDC Health Alert Network #528: multi-country hantavirus cluster linked to Antarctic expedition cruiseMay 8Sanidad EspañaSanidad (Spain): informe de situación brote virus Andes en crucero — un caso confirmado provisionalMay 8RIVMRIVM: 28 Dutch passengers from MV Hondius under home quarantine — GGD contact tracing underwayMay 7Argentina MSalArgentina refuerza la vigilancia epidemiológica de hantavirus tras el brote del MV HondiusMay 6

MV Hondius Cluster — Andes Virus

Andes orthohantavirus (ANDV) · MV Hondius (Ushuaia → Tenerife) → 8 countries · Since April 2026

CONTAINED

All 9 confirmed cases trace back to a single cruise ship. The virus is not spreading on its own.

Confirmed cases
9

+1 in the last 24 hours

Countries reporting
7

Plus close contacts being traced in 6 more

Pandemic risk
8%

Low risk · trend growing

What we're watching next: Watching for the first confirmed case in someone with no link to the cruise ship.
Netherlands — 2 confirmed, 28 close contactsSouth Africa — 1 confirmed, 88 close contactsSwitzerland — 1 confirmedFrance — 1 confirmed, 22 close contactsSpain — 1 confirmed, 14 close contactsUnited Kingdom — 2 confirmed, 30 close contactsUSA — 1 confirmed, 18 close contacts
Confirmed cases
Close contacts being traced

Where the cases are

Confirmed cases and close contacts under surveillance, per country

CountryConfirmedClose contactsSource
🇬🇧United Kingdom
230UKHSA
🇳🇱Netherlands
228RIVM
🇿🇦South Africa
188WHO DON #600
🇫🇷France
122info.gouv.fr
🇺🇸USA
118CDC HAN #528
🇪🇸Spain
114Sanidad
🇨🇭Switzerland
1WHO DON #600
Total92007 countries

How cases are spreading

Every case placed in its transmission generation

9 confirmed (PCR+)
200 close contacts — under surveillance, not yet confirmed
MV Hondius
9confirmed · 100%
+90close contacts · 1000% · awaiting confirmation

Gen 0 — exposure on board · 3 deaths · 1 ICU

9 PCR-confirmed cases among the 147 people aboard the MV Hondius (86 passengers, 61 crew). Source of exposure: rodent contact during shore excursions in Patagonia, with possible person-to-person spread on board. First death at sea on 11 April. 90 additional passengers and crew remain in mandatory 42-day quarantine across NL, ES, GB, and US facilities.

Downstream contacts
0confirmed · 0%
+110close contacts · 1222% · awaiting confirmation

Gen 1 — post-disembarkation flight & airport contacts

110 individuals with a known link to a confirmed case after the ship docked: 88 traced by South African authorities from the 25 April Airlink flight (Saint Helena → Johannesburg), and 22 close contacts in mandatory hospital quarantine in France from the connecting flights to Amsterdam. No Gen 1 case has tested positive at this update.

Note: A “close contact” is someone who had documented close exposure to a confirmed case and is under active surveillance. They are not confirmed infected — they may test negative or remain asymptomatic. This is a standard public health monitoring category, not a confirmed case count.

Pandemic Probability

Score based on Rₜ estimate, geographic reach, immune landscape, and containment signal

8%LOW RISK0100

Outbreak appears contained. All confirmed cases trace to a single source event, the pathogen has limited community transmissibility, and contact tracing is intact. Pandemic risk remains low unless a generation-2 case is confirmed.

Estimated Rₜ ≈ 0.30

Methodology

What this score is. The probability that the outbreak escapes containment and becomes a self-sustaining epidemic in the global population. It is not a transmission-rate calculation.

How it is built. Anchored on a 15% prior — historically, ~5–10% of zoonotic spillover clusters lead to sustained spread, with uncertainty on top. Adjusted by: the pathogen's community R₀ (Andes virus ≈ 0.3 per Martinez et al. 2005), confirmation of Gen 2 transmission, independent introductions, untraced cases, CFR dampening (Lipsitch & Bergstrom 2004), active international response, and time elapsed in surveillance without escape.

What it deliberately does not do. Compute Rₜ from the doubling time of detected cases. For a contained cluster, that doubling reflects contact tracing finding already-infected people, not new transmission — using it would massively overstate risk. Doubling time only enters the score after Gen 2 transmission is confirmed.

Outbreak Watch does not provide medical advice. For health decisions, consult your doctor or your national health authority.